Publications in scientific journals: 2010
Research based on NTR data2010
Aa N van der, Geus EJC de, Beijsterveldt CEM van, Boomsma DI, Bartels M. Genetic influences on individual differences in exercise behavior during adolescence. International Journal of Pediatrics. 2010; Article ID 138345
DOI: 10.1155/2010/138345
Aa N van der, Boomsma DI, Rebollo-Mesa I, Hudziak JJ, Bartels M. Moderation of genetic factors by parental divorce in adolescents' evaluations of family functioning and subjective wellbeing. Twin Research and Human Genetics. 2010;13(2):143-162
DOI: 10.1375/twin.13.2.143
Barsevick A, Frost M, Zwinderman A, Hall P, Halyard M, GENEQOL Consortium: Bartels M, Boomsma DI, many others. I’m so tired: biological and genetic mechanisms of cancer-related fatigue. Quality of Life Research. 2010;19(10):1419-1427
DOI: 10.1007/s11136-010-9757-7
Bartels M, Saviouk V, Moor MHM de, Willemsen G, Beijsterveldt CEM van, Hottenga JJ, Geus EJC de, Boomsma DI. Heritability and genome-wide linkage scan of subjective happiness. Twin Research and Human Genetics. 2010;13(2):135-142
DOI: 10.1375/twin.13.2.135
Beek JHDA van, Willemsen G, Moor MHM de, Hottenga JJ, Boomsma DI. Associations between ADH gene variants and alcohol phenotypes in Dutch adults. Twin Research and Human Genetics. 2010;13(1):30-42
DOI: 10.1375/twin.13.1.30
Beekman M, Nederstigt C, Suchiman HE, Kremer D, Breggen R van der, Lakenberg N, Alemayehu WG, Craen AJ de, Westendorp RG, Boomsma DI, Geus EJC de, Houwing-Duistermaat JJ, Heijmans BT, Slagboom PE. Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity. Proceedings of the National Academy of Sciences of the United States of America. 2010;107(42):18046-18049
DOI: 10.1073/pnas.1003540107
Supplementary Materials (zip file)
Beijsterveldt CEM van, Felsenfeld S, Boomsma DI. Bivariate genetic analyses of stuttering and nonfluency in a large sample of 5-year-old twins. Journal of Speech, Language, and Hearing Research. 2010;53(3):609-619
DOI: 10.1044/1092-4388(2009/08-0202)
Boomsma DI, Saviouk V, Hottenga JJ, Distel MA, Moor MHM de, Vink JM, Geels LM, Beek JHDA van, Bartels M, Geus EJC de, Willemsen G. Genetic epidemiology of attention deficit hyperactivity disorder (ADHD index) in adults. PLoS One. 2010;5(5):e10621, Open Access
DOI: 10.1371/journal.pone.0010621
Braber A den, Ent D van 't, Cath DC, Wagner J, Boomsma DI, Geus EJC de. Brain activation during cognitive planning in twins discordant or concordant for obsessive-compulsive symptoms. Brain. 2010;133(10):3123-3140, Open Access
DOI: 10.1093/brain/awq229
Brans RG, Kahn RS, Schnack HG, Baal GC van, Posthuma D, Haren NE van, Lepage C, Lerch JP, Collins DL, Evans AC, Boomsma DI, Hulshoff Pol HE. Brain plasticity and intellectual ability are influenced by shared genes. The Journal of Neuroscience. 2010;30(16):5519-5524
DOI: 10.1523/JNEUROSCI.5841-09.2010
Brouwer RM, Mandl RC, Peper JS, Baal GC van, Kahn RS, Boomsma DI, Hulshoff Pol HE. Heritability of DTI and MTR in nine-year-old children. Neuroimage. 2010;53(3):1085-1092
DOI: 10.1016/j.neuroimage.2010.03.017
Supplementary Materials (zip file)
Distel MA, Willemsen G, Ligthart L, Derom CA, Martin NG, Neale MC, Trull TJ, Boomsma DI. Genetic covariance structure of the four main features of borderline personality disorder. Journal of Personality Disorders. 2010;24(4):427-444
DOI: 10.1521/pedi.2010.24.4.427
Distel MA, Rebollo-Mesa I, Abdellaoui A, Derom CA, Willemsen G, Cacioppo JT, Boomsma DI. Familial resemblance for loneliness. Behavior Genetics. 2010;40(4):480-494
DOI: 10.1007/s10519-010-9341-5
Draisma HHM, Reijmers TH, Kloet F van der, Bobeldijk-Pastorova I, Spies-Faber E, Vogels JT, Meulman JJ, Boomsma DI, Greef J van der, Hankemeier T. Equating, or correction for between-block effects with application to body fluid LC-MS and NMR metabolomics data sets. Analytical Chemistry. 2010;82(3):1039-1046
DOI: 10.1021/ac902346a
Supplementary Materials (zip file)
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Hottenga JJ, Geus EJC de, Posthuma D, Willemsen G, Penninx BWJH, Boomsma DI, the MAGIC Investigators. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature genetics. 2010;42(2):105-116
DOI: 10.1038/ng.520
Supplementary Materials (zip file)
Eijgelsheim M, Newton-Cheh C, Sotoodehnia N, Bakker PIW de, Müller M, Morrison AC, Smith AV, Isaacs A, Sanna S, Dörr M, Geus EJC de, Hottenga JJ, Pramstaller PP, Duijn CM van, Lakatta EG, Felix SB, Gudnason V, Pfeufer A, Heckbert SR, Stricker BHC, Boerwinkle E, O’Donnell CJ, others. Genome-wide association analysis identifies multiple loci related to resting heart rate. Human Molecular Genetics. 2010;19(19):3885-3894, Open Access
DOI: 10.1093/hmg/ddq303
Supplementary Materials (zip file)
Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Hottenga JJ, Geus EJC de, Willemsen G, Boomsma DI, many others. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genetics. 2010;42(12):1077-1085
DOI: 10.1038/ng.714
Supplementary Materials (zip file)
Ent D van 't, Soelen ILC van, Stam KJ, Geus EJC de, Boomsma DI. Genetic influence demonstrated for MEG-recorded somatosensory evoked responses. Psychophysiology. 2010;47(6):1040-1046
DOI: 10.1111/j.1469-8986.2010.01012.x
Estourgie-Van Burk GF, Bartels M, Boomsma DI, Delemarre-van de Waal HA. Body size of twins compared with siblings and the general population: from birth to late adolescence. The Journal of Pediatrics. 2010;156(4):586-591
DOI: 10.1016/j.jpeds.2009.10.045
Felsenfeld S, Beijsterveldt CEM van, Boomsma DI. Attentional regulation in young twins with probable stuttering, high nonfluency, and typical fluency. The Journal of Speech, Language, and Hearing Research. 2010;53(5):1147-1166
DOI: 10.1044/1092-4388(2010/09-0164)
Franic S, Middeldorp CM, Dolan CV, Ligthart L, Boomsma DI. Childhood and adolescent anxiety and depression: beyond heritability. Journal of the American Academy of Child & Adolescent Psychiatry. 2010;49(8):820-829
DOI: 10.1016/j.jaac.2010.05.013
Freathy RM, Mook-Kanamori DO, Sovio U, Prokopenko I, Timpson NJ, Berry DJ, Warrington NM, Widen E, Hottenga JJ, Kaakinen M, Geus EJC de, Willemsen G, Heinrich J, Gillman MW, Palmer LJ, Frayling TM, Boomsma DI, Davey Smith G, Power C, Jaddoe VWV, Jarvelin MR, McCarthy MI, others. Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics. 2010;42(5):430-435
DOI: 10.1038/ng.567
Supplementary Materials (zip file)
Geus EJC de. From genotype to EEG endophenotype: a route for post-genomic understanding of complex psychiatric disease? Genome Medicine. 2010;2(9):63, Open Access
DOI: 10.1186/gm184
Gielen M, Beijsterveldt CEM van, Derom C, Vlietinck R, Nijhuis JG, Zeegers MP, Boomsma DI. Secular trends in gestational age and birthweight in twins. Human Reproduction. 2010;25(9):2346-2353, Open Access
DOI: 10.1093/humrep/deq160
Supplementary Materials (zip file)
Hart LM ‘t, Simonis-Bik AM, Nijpels G, Haeften TW van, Schafer SA, Boomsma DI, Slagboom PE, Willemsen G, Eekhoff EM, Geus EJC de, Dekker JM, Fritsche A, others. Combined risk allele score of eight type 2 diabetes genes is associated with reduced first-phase glucose-stimulated insulin secretion during hyperglycemic clamps. Diabetes. 2010;59(1):287-292
DOI: 10.2337/db09-0736
Haworth CM, Wright MJ, Luciano M, Martin NG, Geus EJC de, Beijsterveldt CEM van, Bartels M, Posthuma D, Boomsma DI, Iacono WG, Hart SA, Petrill SA, Lubinski D, Plomin R, others. The heritability of general cognitive ability increases linearly from childhood to young adulthood. Molecular Psychiatry. 2010;15(11):1112-1120
DOI: 10.1038/mp.2009.55
Supplementary Materials (zip file)
Heid IM, Jackson AU, Randall JC, Winkler TW, Qi L, Speliotes EK, Magi R, Workalemahu T, Esko T, Nyholt DR, Visscher PM, Hottenga JJ, Prokopenko I, Surakka I, Sandholt C, Scott LJ, Geus EJC de, Willemsen G, Boomsma DI, many others. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nature Genetics. 2010;42(11):949-60
DOI: 10.1038/ng.685
Supplementary Materials (zip file)
Heni M, Ketterer C, Hart LM, Ranta F, Haeften TW van, Eekhoff EM, Dekker JM, Boomsma DI, Nijpels G, Kramer MH, Diamant M, Simonis-Bik AM, Heine RJ, Geus EJC de, Schafer SA, Machicao F, Ullrich S, Thamer C, Stefan N, Staiger H, Haring HU, Fritsche A. The impact of genetic variation in the G6PC2 gene on insulin secretion depends on glycemia. The Journal of Clinical Endocrinology & Metabolism. 2010;95(12):E479-484, Open Access
DOI: 10.1210/jc.2010-0860
Supplementary Materials (zip file)
Hoekstra C, Willemsen G, Beijsterveldt CEM van, Lambalk CB, Montgomery GW, Boomsma DI. Body composition, smoking, and spontaneous dizygotic twinning. Fertility and Sterility. 2010;93(3):885-893
DOI: 10.1016/j.fertnstert.2008.10.012
Jonker MA, Boomsma DI. A frailty model for (interval) censored family survival data, applied to the age at onset of non-physical problems. Lifetime Data Analysis. 2010;16(3):299-315, Open Access
DOI: 10.1007/s10985-009-9141-5
Lamb DJ, Middeldorp CM, Beijsterveldt CEM van, Bartels M, Aa N van der, Polderman TJC, Boomsma DI. Heritability of anxious-depressive and withdrawn behavior: age-related changes during adolescence. Journal of the American Academy of Child & Adolescent Psychiatry. 2010;49(3):248-255
DOI: 10.1016/j.jaac.2009.11.014
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Hottenga JJ, Levinson DF, Lorentzon M, McKnight B, Morris AP, Muller M, Suh Ngwa J, Purcell S, Geus EJC de, Willemsen G, Boomsma DI, many others. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 2010;467(7317):832-838
DOI: 10.1038/nature09410
Supplementary Materials (zip file)
Licht CMM, Vreeburg SA, Reedt Dortland AKB van, Giltay EJ, Hoogendijk WJG, DeRijk RH, Vogelzangs N, Zitman FG, Geus EJC de, Penninx BWJH. Increased Sympathetic and Decreased Parasympathetic Activity Rather Than Changes in Hypothalamic-Pituitary-Adrenal Axis Activity Is Associated with Metabolic Abnormalities. The Journal of Clinical Endocrinology & Metabolism. 2010;95(5):2458-2466, Open Access
DOI: 10.1210/jc.2009-2801
Ligthart L, Nyholt DR, Penninx BWJH, Boomsma DI. The shared genetics of migraine and anxious depression. Headache. 2010;50(10):1549-1560, Open Access
DOI: 10.1111/j.1526-4610.2010.01705.x
Ligthart L, Penninx BWJH, Nyholt DR, Distel MA, Geus EJC de, Willemsen G, Smit JH, Boomsma DI. Migraine symptomatology and major depressive disorder. Cephalalgia. 2010;30(9):1073-1081
DOI: 10.1177/0333102410363492
Lind PA, Macgregor S, Vink JM, Pergadia ML, Hansell NK, Moor MHM de, Smit AB, Hottenga JJ, Richter MM, Heath AC, Martin NG, Willemsen G, Geus EJC de, Vogelzangs N, Penninx BWJH, Whitfield JB, Montgomery GW, Boomsma DI, Madden PA. A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations. Twin Research and Human Genetics. 2010;13(1):10-29
DOI: https://doi.org/10.1017/S183242740002003X
Middeldorp CM, Vink JM, Hettema JM, Geus EJC de, Kendler KS, Willemsen G, Neale MC, Boomsma DI, Chen X. An association between Epac-1 gene variants and anxiety and depression in two independent samples. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2010;153B(1):214-219
DOI: 10.1002/ajmg.b.30976
Middeldorp CM, Geus EJC de, Willemsen G, Hottenga JJ, Slagboom PE, Boomsma DI. The serotonin transporter gene length polymorphism (5-HTTLPR) and life events: no evidence for an interaction effect on neuroticism and anxious depressive symptoms. Twin Research and Human Genetics. 2010;13(6):544-549
DOI: 10.1375/twin.13.6.544
Middeldorp CM, Slof-Op 't Landt MC, Medland SE, Beijsterveldt CEM van, Bartels M, Willemsen G, Hottenga JJ, Geus EJC de, Suchiman HED, Dolan CV, Neale MC, Slagboom PE, Boomsma DI. Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes? Genes, Brain and Behavior. 2010;9(7):808-816, Open Access
DOI: 10.1111/j.1601-183X.2010.00619.x
Supplementary Materials (zip file)
Minica CC, Boomsma DI, Sluis S van der, Dolan CV. Genetic association in multivariate phenotypic data: power in five models. Twin Research and Human Genetics. 2010;13(6):525-543
DOI: 10.1375/twin.13.6.525
Naukkarinen J, Surakka I, Pietiläinen KH, Rissanen A, Salomaa V, Ripatti S, Yki-Järvinen H, Duijn CM van, Wichmann H-E, Kaprio J, Taskinen M-R, Peltonen L, ENGAGE Consortium. Use of Genome-Wide Expression Data to Mine the "Gray Zone" of GWA Studies Leads to Novel Candidate Obesity Genes. PLoS ONE. 2010;6(6):e100976, Open Access
DOI: 10.1371/journal.pgen.1000976
Supplementary Materials (zip file)
Nettleton JA, McKeown NM, Kanoni S, Lemaitre RN, Hivert M-F, Ngwa J, Rooij FJA van, Sonestedt E, Wojczynski MK, Ye Z, Tanaka T, The CHARGE Whole Grain Foods Study Group. Interactions of Dietary Whole-Grain Intake With Fasting Glucose– and Insulin-Related Genetic Loci in Individuals of European Descent. Diabetes Care. 2010;33(12):2684-2691
DOI: 10.2337/dc10-1150
Supplementary Materials (zip file)
Painter JN, Willemsen G, Nyholt DR, Hoekstra C, Duffy DL, Henders AK, Wallace L, Healey S, Cannon-Albright LA, Skolnick M, Martin NG, Boomsma DI, Montgomery GW. A genome wide linkage scan for dizygotic twinning in 525 families of mothers of dizygotic twins. Human Reproduction. 2010;25(6):1569-1580, Open Access
DOI: 10.1093/humrep/deq084
Peper JS, Brouwer RM, Leeuwen M van, Schnack HG, Boomsma DI, Kahn RS, Hulshoff Pol HE. HPG-axis hormones during puberty: a study on the association with hypothalamic and pituitary volumes. Psychoneuroendocrinology. 2010;35(1):133-140
DOI: 10.1016/j.psyneuen.2009.05.025
Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Penninx BWJH, Boomsma DI, Middeldorp CM, Bass N, McQuillin A, Hamshere M, Craddock N, Sklar P, Smoller JW, others. Genome-wide association study of suicide attempts in mood disorder patients. The American Journal of Psychiatry. 2010;167(12):1499-1507
DOI: 10.1176/appi.ajp.2010.10040541
Supplementary Materials (zip file)
Petrides KV, Vernon PA, Schermer JA, Ligthart L, Boomsma DI, Veselka L. Relationships between trait emotional intelligence and the Big Five in the Netherlands. Personality and Individual Differences. 2010;48(8):906-910
DOI: 10.1016/j.paid.2010.02.019
Polderman TJC, Boomsma DI, Bartels M, Verhulst FC, Huizink AC. A systematic review of prospective studies on attention problems and academic achievement. Acta Psychiatrica Scandinavica. 2010;122(4):271-284
DOI: 10.1111/j.1600-0447.2010.01568.x
Polderman TJC, Bartels M, Verhulst FC, Huizink AC, Beijsterveldt CEM van, Boomsma DI. No effect of classroom sharing on educational achievement in twins: a prospective, longitudinal cohort study. Journal of Epidemiology & Community Health. 2010;64(1):36-40
DOI: 10.1136/jech.2009.091629
Reiling E, Ling C, Uitterlinden AG, Riet E van't, Welschen LM, Ladenvall C, Almgren P, Lyssenko V, Nijpels G, Hove EC van, Maassen JA, Geus EJC de, Boomsma DI, Dekker JM, Groop L, Willemsen G, Hart LM ‘t. The association of mitochondrial content with prevalent and incident type 2 diabetes. The Journal of Clinical Endocrinology & Metabolism. 2010;95(4):1909-1915, Open Access
DOI: 10.1210/jc.2009-1775
Robbers SCC, Bartels M, Oort FV van, Beijsterveldt CEM van, Ende J van der, Verhulst FC, Boomsma DI, Huizink AC. A twin-singleton comparison of developmental trajectories of externalizing and internalizing problems in 6- to 12-year-old children. Twin Research and Human Genetics. 2010;13(1):79-87
DOI: 10.1375/twin.13.1.79
Schot AC van der, Vonk R, Brouwer RM, Baal GCM van, Brans RG, Haren NE van, Schnack HG, Boomsma DI, Nolen WA, Hulshoff Pol HE, Kahn RS. Genetic and environmental influences on focal brain density in bipolar disorder. Brain. 2010;133(10):3080-3092, Open Access
DOI: 10.1093/brain/awq236
Supplementary Materials (zip file)
Shi Q, Cleeland CS, Klepstad P, Miaskowski C, Pedersen NL, GeneQOL Consortium, Abernethy AP, Baas F, Barsevick AM, Bartels M, Boomsma DI, Sprangers MA, Veenhoven R, Yang P, Zwinderman AH, others. Biological pathways and genetic variables involved in pain. Quality of Life Research. 2010;19(10):1407-1417
DOI: 10.1007/s11136-010-9738-x
Simonis-Bik AM, Nijpels G, Haeften TW van, Houwing-Duistermaat JJ, Boomsma DI, Reiling E, Hove EC van, Diamant M, Kramer MH, Heine RJ, Maassen JA, Slagboom PE, Willemsen G, Dekker JM, Eekhoff EM, Geus EJC de, Hart LM ‘t. Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function. Diabetes. 2010;59(1):293-301
DOI: 10.2337/db09-1048
Sluis S van der, Vinkhuyzen AAE, Boomsma DI, Posthuma D. Sex differences in adults' motivation to achieve. Intelligence. 2010;38(4):433-446
DOI: 10.1016/j.intell.2010.04.004
Smit DJA, Luciano M, Bartels M, Beijsterveldt CEM van, Wright MJ, Hansell NK, Brunner HG, Estourgie-Van Burk GF, Geus EJC de, Martin NG, Boomsma DI. Heritability of head size in Dutch and Australian twin families at ages 0-50 years. Twin Research and Human Genetics. 2010;13(4):370-380
DOI: 10.1375/twin.13.4.370
Smit DJA, Boersma M, Beijsterveldt CEM van, Posthuma D, Boomsma DI, Stam CJ, Geus EJC de. Endophenotypes in a dynamically connected brain. Behavior Genetics. 2010;40(2):167-177, Open Access
DOI: 10.1007/s10519-009-9330-8
Soelen ILC van, Brouwer RM, Peper JS, Beijsterveldt CEM van, Leeuwen M van, Vries LS de, Kahn RS, Hulshoff Pol HE, Boomsma DI. Effects of gestational age and birth weight on brain volumes in healthy 9 year-old children. The Journal of Pediatrics. 2010;156(6):896-901
DOI: 10.1016/j.jpeds.2009.12.052
Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Boomsma DI, Geus EJC de, Hottenga JJ, many others. Common variants at 10 genomic loci influence hemoglobin A(C) levels via glycemic and nonglycemic pathways. Diabetes. 2010;59(12):3229-3239
DOI: 10.2337/db10-0502
Supplementary Materials (zip file)
Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Lango Allen H, Lindgren CM, Luan J, Mägi R, Hottenga JJ, Geus EJC de, MAGIC, Willemsen G, Boomsma DI, Penninx BWJH, Abecasis GR, Barroso I, Boehnke M, Stefansson K, North KE, McCarthy MI, Hirschhorn JN, Ingelsson E, Loos RJF, many others on behalf of GIANT. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nature Genetics. 2010;42(11):937-948
DOI: 10.1038/ng.686
Supplementary Materials (zip file)
Sprangers MAG, Sloan JA, Barsevick A, Chauhan C, Dueck AC, Raat H, Shi Q, Noorden CJF van, Bartels M, Boomsma DI, GENEQOL Consortium. Scientific imperatives, clinical implications, and theoretical underpinnings for the investigation of the relationship between genetic variables and patient-reported quality-of-life outcomes. Quality of Life Research. 2010;19(10):1395-1403, Open Access
DOI: 10.1007/s11136-010-9759-5
Sprangers MAG, Bartels M, Veenhoven R, Baas F, Martin NG, Mosing M, Movsas B, Ropka ME, Shinozaki G, Swaab D, Boomsma DI, The GENEQOL Consortium. Which patient will feel down, which will be happy? The need to study the genetic disposition of emotional states. Quality of Life Research. 2010;19(10):1429-1437, Open Access
DOI: 10.1007/s11136-010-9652-2
Talens RP, Boomsma DI, Tobi EW, Kremer D, Jukema JW, Willemsen G, Putter H, Slagboom PE, Heijmans BT. Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. The Faseb Journal. 2010;24(9):3135-3144
DOI: 10.1096/fj.09-150490
Supplementary Materials (zip file)
Terracciano A, Sanna S, Uda M, Deiana B, Usala G, Busonero F, Maschio A, Scally M, Patriciu N, Chen WM, Distel MA, Slagboom EP, Boomsma DI, Burmeister M, Amin N, Janssens AC, Duijn CM van, Schlessinger D, Abecasis GR, Costa Jr PT. Genome-wide association scan for five major dimensions of personality. Molecular Psychiatry. 2010;15(6):647-656
DOI: 10.1038/mp.2008.113
Supplementary Materials (zip file)
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Willemsen G, Penninx BWJH, Hottenga JJ, Geus EJC de, Boomsma DI, Duijn CM van, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S, many others. Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids. Nature. 2010;466(7307):707-713
DOI: 10.1038/nature09270
Supplementary Materials (zip file)
Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Hottenga JJ, Willemsen G, Penninx BWJH, Oostra BA, Boomsma DI, Tiemeier H, Duijn CM van, Kaprio J, Gulcher JR, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K, many others. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nature Genetics. 2010;42(5):448-453
DOI: 10.1038/ng.573
Supplementary Materials (zip file)
The Tobacco and Genetics Consortium, Furberg H, Kim YJ, Dackor J, Boerwinkle E, Franceschini N, Ardissino D, Bernardinelli L, Mannucci PM, Boomsma DI, Geus EJC de, Vink JM, Willemsen G, Tiemeier H, Uitterlinden AG, Duijn CM van, Maes HH, Posthuma D, Kaprio J, Rose JE, Ioannidis JPA, Kraft P, Lin D-Y, Sullivan PF, many others. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nature Genetics. 2010;42(5):441-447
DOI: 10.1038/ng.571
Supplementary Materials (zip file)
Verweij KJ, Zietsch BP, Lynskey MT, Medland SE, Neale MC, Martin NG, Boomsma DI, Vink JM. Genetic and environmental influences on cannabis use initiation and problematic use: a meta-analysis of twin studies. Addiction. 2010;105(3):417-430
DOI: 10.1111/j.1360-0443.2009.02831.x
Vink JM, Wolters LM, Neale MC, Boomsma DI. Heritability of cannabis initiation in Dutch adult twins. Addictive Behaviors. 2010;35(2):172-174
DOI: 10.1016/j.addbeh.2009.09.015
Vinkhuyzen AAE, Sluis S van der, Geus EJC de, Boomsma DI, Posthuma D. Genetic influences on 'environmental' factors. Genes, Brain and Behavior. 2010;9(3):276-287, Open Access
DOI: 10.1111/j.1601-183X.2009.00554.x
Vinkhuyzen AAE, Sluis S van der, Boomsma DI, Geus EJC de, Posthuma D. Individual differences in processing speed and working memory speed as assessed with the Sternberg memory scanning task. Behavior Genetics. 2010;40(3):315-326, Open Access
DOI: 10.1007/s10519-009-9315-7
Willemsen G, Geus EJC de, Bartels M, Beijsterveldt CEM van, Brooks AI, Estourgie-Van Burk GF, Fugman DA, Hoekstra C, Hottenga JJ, Kluft K, Meijer P, Montgomery GW, Rizzu P, Sondervan D, Smit AB, Spijker S, Suchiman HED, Tischfield JA, Lehner T, Slagboom PE, Boomsma DI. The Netherlands Twin Register Biobank: A Resource for Genetic Epidemiological Studies. Twin Research and Human Genetics. 2010;13(3):231-245
DOI: 10.1375/twin.13.3.231
Wu T, Snieder H, Geus EJC de. Genetic influences on cardiovascular stress reactivity. Neuroscience & Biobehavioral Reviews. 2010;35(1):58-68
DOI: 10.1016/j.neubiorev.2009.12.001
Wu T, Boezen HM, Postma DS, Los H, Postmus PE, Snieder H, Boomsma DI. Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins. European Respiratory Journal. 2010;36(2):261
DOI: 10.1183/09031936.00123909
Zwijnenburg PJ, Meijers-Heijboer H, Boomsma DI. Identical but not the same: the value of discordant monozygotic twins in genetic research. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2010;153B(6):1134-1149
DOI: 10.1002/ajmg.b.31091